public event CellBeginEditEventHandler CellBeginEdit

Public Event CellBeginEdit As CellBeginEditEventHandler

<Grid>
        <dxs:SpreadsheetControl x:Name="spreadsheetControl"
                                DocumentSource="pack://application:,,,/Spreadsheet WPF;component/Products.xlsx"             
                                CommandBarStyle="Ribbon" 
                                ShowFormulaBar="True" 
                                ShowStatusBar="True"
                                CellBeginEdit="SpreadsheetControl1_CellBeginEdit"
                                CellEndEdit="SpreadsheetControl1_CellEndEdit"
                                CellValueChanged="SpreadsheetControl1_CellValueChanged" />
    </Grid>

private CultureInfo CurrentCulture => spreadsheetControl.Options.Culture;

private void SpreadsheetControl1_CellBeginEdit(object sender, SpreadsheetCellCancelEventArgs e)
{
    // Allow users to edit cells only in the 'Unit Price' and 'Units in Stock' columns.
    if (e.Cell.ColumnIndex < 2 || e.Cell.ColumnIndex > 3 || e.Cell.RowIndex < 1 || e.Cell.RowIndex > 19)
    {
        e.Cancel = true;
        MessageBox.Show("You can edit only the 'Unit Price' and 'Units in Stock' values.", "Warning", MessageBoxButtons.OK);
    }
}

private void SpreadsheetControl1_CellEndEdit(object sender, SpreadsheetCellValidatingEventArgs e)
{
    // Validate a value that a user enters into a cell.
    string editorText = e.EditorText;
    bool validValue = e.Cell.ColumnIndex == 2 ? ValidateUnitPrice(editorText) : ValidateUnitsInStock(editorText);
    if (!validValue)
    {
        e.Cancel = true;
        MessageBox.Show("The value you entered is invalid.", "Warning", MessageBoxButtons.OK);
    }
}

private bool ValidateUnitPrice(string text)
{
    // Validate values in the 'Unit Price' column.
    // Convert the obtained string to a Double value. 
    bool conversionResult = double.TryParse(text, NumberStyles.AllowDecimalPoint, CurrentCulture, out double result);
    return conversionResult && result > 0;
}

private bool ValidateUnitsInStock(string text)
{
    // Validate values in the 'Units in Stock' column.
    // Convert the obtained string to an integer value. 
    return int.TryParse(text, NumberStyles.None, CurrentCulture, out int result);
}

private void SpreadsheetControl1_CellValueChanged(object sender, SpreadsheetCellEventArgs e)
{
    if (e.Cell.ColumnIndex != 3)
        return;
    // Highlight zero values in the 'Units in Stock' column.
    e.Cell.FillColor = (e.Value.NumericValue == 0) ? Color.LightPink : Color.White;
}

Private ReadOnly Property CurrentCulture() As CultureInfo
  Get
    Return spreadsheetControl.Options.Culture
  End Get
End Property

Private Sub SpreadsheetControl1_CellBeginEdit(ByVal sender As Object, ByVal e As SpreadsheetCellCancelEventArgs)
  ' Allow users to edit cells only in the 'Unit Price' and 'Units in Stock' columns.
  If e.Cell.ColumnIndex < 2 OrElse e.Cell.ColumnIndex > 3 OrElse e.Cell.RowIndex < 1 OrElse e.Cell.RowIndex > 19 Then
    e.Cancel = True
    MessageBox.Show("You can edit only the 'Unit Price' and 'Units in Stock' values.", "Warning", MessageBoxButtons.OK)
  End If
End Sub

Private Sub SpreadsheetControl1_CellEndEdit(ByVal sender As Object, ByVal e As SpreadsheetCellValidatingEventArgs)
  ' Validate a value that a user enters into a cell.
  Dim editorText As String = e.EditorText
  Dim validValue As Boolean = If(e.Cell.ColumnIndex = 2, ValidateUnitPrice(editorText), ValidateUnitsInStock(editorText))
  If Not validValue Then
    e.Cancel = True
    MessageBox.Show("The value you entered is invalid.", "Warning", MessageBoxButtons.OK)
  End If
End Sub

Private Function ValidateUnitPrice(ByVal text As String) As Boolean
  ' Validate values in the 'Unit Price' column.
  ' Convert the obtained string to a Double value. 
  Dim result As Double
  Dim conversionResult As Boolean = Double.TryParse(text, NumberStyles.AllowDecimalPoint, CurrentCulture, result)
  Return conversionResult AndAlso result > 0
End Function

Private Function ValidateUnitsInStock(ByVal text As String) As Boolean
  ' Validate values in the 'Units in Stock' column.
  ' Convert the obtained string to an integer value. 
  Dim result As Integer
  Return Integer.TryParse(text, NumberStyles.None, CurrentCulture, result)
End Function

Private Sub SpreadsheetControl1_CellValueChanged(ByVal sender As Object, ByVal e As SpreadsheetCellEventArgs)
  If e.Cell.ColumnIndex <> 3 Then
    Return
  End If
  ' Highlight zero values in the 'Units in Stock' column.
  e.Cell.FillColor = If(e.Value.NumericValue = 0, Color.LightPink, Color.White)
End Sub