public event LegendItemCheckedEventHandler LegendItemChecked

Public Event LegendItemChecked As LegendItemCheckedEventHandler

using DevExpress.Drawing;
using DevExpress.XtraCharts;
using System;
using System.Drawing;
using System.Windows.Forms;

namespace CustomCheckboxesInLegendViewAndBehavior {
    public partial class mainForm : Form {
        const int LegendRadioSide = 17;
        const int LegendRadioInnerPointBoundsSide = 8;
        const float LegendRadioWidth = 1.5f;
        bool initializationFlag = false;

        public mainForm() {
            InitializeComponent();
            chartControl.BeginInit(); {
                chartControl.LegendItemChecked += OnLegendItemChecked;
                chartControl.CustomDrawSeries += OnCustomDrawSeries;
                chartControl.Legend.UseCheckBoxes = true;
                chartControl.Series["Point"].CheckedInLegend = false;
                chartControl.Series["Line"].CheckedInLegend = true;
                chartControl.Series["Area"].CheckedInLegend = false;
            }
            chartControl.EndInit();
            initializationFlag = false;
        }

        void OnLegendItemChecked(object sender, LegendItemCheckedEventArgs e) {
            if (initializationFlag == true)
                return;
            initializationFlag = true; {
                Series checkedSeries = e.CheckedElement as Series;
                if (checkedSeries == null)
                    throw new Exception("Expected series only");
                foreach (Series series in chartControl.Series)
                    series.CheckedInLegend = false;
                checkedSeries.CheckedInLegend = true;
                chartControl.Titles[0].Text = checkedSeries.Name;
            }
            initializationFlag = false;
        }

        void OnCustomDrawSeries(object sender, CustomDrawSeriesEventArgs e) {
            DXBitmap bitmap = new DXBitmap(LegendRadioSide, LegendRadioSide);
            using (DXGraphics graphics = DXGraphics.FromImage(bitmap)) {
                graphics.SmoothingMode = DXSmoothingMode.HighQuality;
                Color seriesColor = GetSeriesColor(e.Series, chartControl);
                using (DXPen radioPen = new DXPen(seriesColor, LegendRadioWidth)) {
                    int radioRadius = LegendRadioSide - 3;
                    Rectangle radioRectangle = new Rectangle(1, 1, radioRadius, radioRadius);
                    graphics.DrawEllipse(radioPen, radioRectangle);
                }
                if (e.Series.CheckedInLegend) {
                    using (DXBrush brush = new DXSolidBrush(seriesColor)) {
                        int coord = (LegendRadioSide - LegendRadioInnerPointBoundsSide) / 2;
                        Rectangle filledEllipseBounds = new Rectangle(coord, coord,
                              LegendRadioInnerPointBoundsSide, LegendRadioInnerPointBoundsSide);
                        graphics.FillEllipse(brush, filledEllipseBounds);
                    }
                }
            }
            e.DisposeLegendMarkerImage = true;
            e.DXLegendMarkerImage = bitmap;
        }

        Color GetSeriesColor(Series series, ChartControl chartControl) {
            int seriesIndex = chartControl.Series.IndexOf(series);
            string paletteName = chartControl.PaletteName;
            Palette currentPalette = chartControl.PaletteRepository[paletteName];
            PaletteEntry paletteEntryAccordingToSeries = currentPalette[seriesIndex];
            Color result = paletteEntryAccordingToSeries.Color;
            return result;
        }
    }
}

Imports DevExpress.Drawing
Imports DevExpress.XtraCharts
Imports System
Imports System.Drawing
Imports System.Windows.Forms

Namespace CustomCheckboxesInLegendViewAndBehavior

    Public Partial Class mainForm
        Inherits Form

        Const LegendRadioSide As Integer = 17

        Const LegendRadioInnerPointBoundsSide As Integer = 8

        Const LegendRadioWidth As Single = 1.5F

        Private initializationFlag As Boolean = False

        Public Sub New()
            InitializeComponent()
            chartControl.BeginInit()
            If True Then
                AddHandler chartControl.LegendItemChecked, AddressOf OnLegendItemChecked
                AddHandler chartControl.CustomDrawSeries, AddressOf OnCustomDrawSeries
                chartControl.Legend.UseCheckBoxes = True
                chartControl.Series("Point").CheckedInLegend = False
                chartControl.Series("Line").CheckedInLegend = True
                chartControl.Series("Area").CheckedInLegend = False
            End If

            chartControl.EndInit()
            initializationFlag = False
        End Sub

        Private Sub OnLegendItemChecked(ByVal sender As Object, ByVal e As LegendItemCheckedEventArgs)
            If initializationFlag = True Then Return
            initializationFlag = True
            If True Then
                Dim checkedSeries As Series = TryCast(e.CheckedElement, Series)
                If checkedSeries Is Nothing Then Throw New Exception("Expected series only")
                For Each series As Series In chartControl.Series
                    series.CheckedInLegend = False
                Next

                checkedSeries.CheckedInLegend = True
                chartControl.Titles(0).Text = checkedSeries.Name
            End If

            initializationFlag = False
        End Sub

        Private Sub OnCustomDrawSeries(ByVal sender As Object, ByVal e As CustomDrawSeriesEventArgs)
            Dim bitmap As DXBitmap = New DXBitmap(LegendRadioSide, LegendRadioSide)
            Using graphics As DXGraphics = DXGraphics.FromImage(bitmap)
                graphics.SmoothingMode = DXSmoothingMode.HighQuality
                Dim seriesColor As Color = GetSeriesColor(e.Series, chartControl)
                Using radioPen As DXPen = New DXPen(seriesColor, LegendRadioWidth)
                    Dim radioRadius As Integer = LegendRadioSide - 3
                    Dim radioRectangle As Rectangle = New Rectangle(1, 1, radioRadius, radioRadius)
                    graphics.DrawEllipse(radioPen, radioRectangle)
                End Using

                If e.Series.CheckedInLegend Then
                    Using brush As DXBrush = New DXSolidBrush(seriesColor)
                        Dim coord As Integer =(LegendRadioSide - LegendRadioInnerPointBoundsSide) \ 2
                        Dim filledEllipseBounds As Rectangle = New Rectangle(coord, coord, LegendRadioInnerPointBoundsSide, LegendRadioInnerPointBoundsSide)
                        graphics.FillEllipse(brush, filledEllipseBounds)
                    End Using
                End If
            End Using

            e.DisposeLegendMarkerImage = True
            e.DXLegendMarkerImage = bitmap
        End Sub

        Private Function GetSeriesColor(ByVal series As Series, ByVal chartControl As ChartControl) As Color
            Dim seriesIndex As Integer = chartControl.Series.IndexOf(series)
            Dim paletteName As String = chartControl.PaletteName
            Dim currentPalette As Palette = chartControl.PaletteRepository(paletteName)
            Dim paletteEntryAccordingToSeries As PaletteEntry = currentPalette(seriesIndex)
            Dim result As Color = paletteEntryAccordingToSeries.Color
            Return result
        End Function
    End Class
End Namespace

chartControl.BeginInit(); {
    chartControl.LegendItemChecked += OnLegendItemChecked;
    chartControl.CustomDrawSeries += OnCustomDrawSeries;

If True Then
    AddHandler chartControl.LegendItemChecked, AddressOf OnLegendItemChecked
    AddHandler chartControl.CustomDrawSeries, AddressOf OnCustomDrawSeries